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Identification

Description


Principaux synonymes

Noms français :

  • Alcalase
  • BACILLOPEPTIDASE A
  • BACILLOPEPTIDASE B
  • BACILLUS SUBTILIS ALKALINE PROTEASE
  • EC 3.4.21.14
  • EC 3.4.4.16
  • MAXATASE
  • Subtilisine (9014-01-1)
  • Subtilisines
  • SUBTILISINES (9014-01-1)
  • SUBTILOPEPTIDASE A
  • SUBTILOPEPTIDASE B
  • SUBTILOPEPTIDASE C

Noms anglais :

  • Subtilisin (9014-01-1)
  • Subtilisins
  • SUBTILISINS (9014-01-1)
  • Subtilisins [9014-01-1], as 100% crystalline active pure enzyme
Utilisation et sources d'émission

Fabrication de détergents

Références

  • ▲1.  Drolet, D. et Beauchamp, G, Guide d'échantillonnage des contaminants de l'air en milieu de travail. Études et recherches / Guide technique, 8ème éd. revue et mise à jour. Montréal : IRSST. (2012). T-06. [MO-220007]   http://www.irsst.qc.ca
    http://www.irsst.qc.ca/files/documents/PubIRSST/t-06.pdf
  • ▲2.  HERA (Human and Environmental Risk Assessment on ingredients of household cleaning products), Subtilisins (Protease); C.A.S No: 9014-01-1, 1395-21-7, 9073-77-2, 9001-92-7, 79986-26-8, 95979-76-3, 68909-17-1. (2007).   http://www.heraproject.com/RiskAssessment.cfm?SUBID=22
    https://www.heraproject.com/files/22-F-07_PROTEASE_HERA_Final%20Edition%20(unsecured%20-%20PDFA-1b).pdf Edition (unsecured - PDFA-1b).pdf
  • ▲3.  ECHA (European Chemicals Agency) , Information on Chemicals (REACH). Helsinki, Finland.   http://echa.europa.eu/information-on-chemicals/registered-substances
  • ▲4.  Griffith J.F., Weaver J.E. et Whitehouse H.S., «Safety evaluation of enzyme detergents : oral and cutaneous toxicity, irritancy and skin sensitization studies.» Food and cosmetics toxicology. Vol. 7, p. 581-593. (1969). [AP-000941]
  • ▲5.  American Conference of Governmental Industrial Hygienists, «Subtilisins.» In: Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. Cincinnati, Ohio : ACGIH. (2001). Publication #0100Doc.   http://www.acgih.org
  • ▲6.  National Library of Medicine, The Hazardous Substances Data Bank (HSDB). Hamilton (Ont.) : Canadian Centre for Occupational Health and Safety.   http://www.ccohs.ca/
  • ▲7.  Pepys J., et al., «Allergic reactions of the lungs to enzymes of bacillus subtilis.» Lancet. Vol. 1, p. 1181-1184. (1969). [AP-021233]
  • ▲8.  Radermecker, M. et Booz, J., «À propos de trois cas d'asthme secondaire à une sensibilisation à des enzymes protéolytiques de Bacillus subtilis.» Acta Tuberculosa et Pneumologica Belgica. Vol. 61, no. 5-6, p. 465-470. (1970). [AP-030675]
  • ▲9.  Dijkman, J.H. et al., «Allergic bronchial reactions to inhalation of enzymes of Bacillus subtilis .» American Review of Respiratory Disease. Vol. 107, p. 387-394. (1973). [AP-034719]
  • ▲10.  Shapiro, R.S. et Eisenberg, B.C., «Sensitivity to proteolytic enzymes in laundry detergents.» Journal of Allergy. Vol. 47, no. 2, p. 76-79. (1971). [AP-031485]
  • ▲11.  Slavin, R.G. et Lewis C.R., «Hypersensitivity to enzyme additives in laundry detergents workers.» Journal of Laboratory and Clinical Medicine. Vol. 78, no. 6, p. 977-978. (1971).
  • ▲12.  Wuthrich, B. et Schwarz-Speck, M., «Bronchial asthma following occupational exposure to proteolytic enzymes (Bacillus subtilis proteases).» Schweizerische Medizinische Wochenschrift. Vol. 100, no. 45, p. 1908-1914. (1970). [AP-059617]
  • ▲13.  Reinheimer, W. et Utz, G., «Allergic bronchial asthma due to maxatase, a proteolytic enzyme added to washing powder.» Deutsche Medizinische Wochenschrift. Vol. 96, no. 6, p. 246-247. (1971). [AP-059616]
  • ▲14.  Pepys. J., «Immunologic and clinical findings in workers and consumers exposed to the enzymes of Bacillus subtilis.» Proceedings. Royal Society of Medicine. Vol. 66, no. 9, p. 16-18. (1973). [AP-059610]
  • ▲15.  Rodriguez, A. et al., «Occupational asthma due to Bacillus subtilis enzymes in a bakery worker.» Journal on Investigational Allergology & Clinical Immunology. Vol. 7, no. 5, p. 453. (1997). [AP-059609]
  • ▲16.  Greenberg, M., Milne, J.F. et Watt, A., «Survey of workers exposed to dusts containing derivatives of Bacillus subtilis.» British Medical Journal. Vol. 2, p. 629-633. (1970). [AP-59608]
  • ▲17.  Pepys, J. et al., «Clinical and immunological responses to enzymes of Bacillus subtilis in factory workers and consumers.» Clinical Allergy. Vol. 3, p. 143-160. (1973). [AP-030334]
  • ▲18.  Franz, T. et al., «Clinical, immunologic, and physiologic observations in factory workers exposed to B. subtilis enzyme dust.» Journal of Allergy. Vol. 47, no. 3, p. 170-180. (1971).
  • ▲19.  Mitchell, C.A. et Gandevia, B., «Respiratory symptoms and skin reactivity in workers exposed to proteolytic enzymes in the detergent industry.» American Review of Respiratory Disease. Vol. 104, p. 1-12. (1971). [AP-034718]
  • ▲20.  Smith, D.J., Mathias, C.G. et Greenwald, D.I., «Contact dermatitis from B. subtilis-derived protease enzymes.» Contact Dermatitis. Vol. 20, no. 1, p. 58-59. (1989).
  • ▲21.  National Industrial Chemicals Notification and Assessment Scheme, Savinase- Proteolytic enzymes in detergents . Priority Existing Chemical. Canberra, Australia : NICNAS. (1992). PEC 2.   https://www.nicnas.gov.au/__data/assets/word_doc/0004/34807/PEC2-savinase.docx
  • ▲22.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
  • ▲23.  Règlement sur la santé et la sécurité du travail [S-2.1, r. 13]. Québec : Éditeur officiel du Québec. [RJ-510071]   http://legisquebec.gouv.qc.ca/fr/ShowDoc/cr/S-2.1,%20r.%2013

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