Identification

Description


Formule moléculaire brute : C4H9NO

Principaux synonymes

Noms français :

  • ACETAMIDE, N,N-DIMETHYL-
  • ACETIC ACID DIMETHYLAMIDE
  • DIMETHYL ACETAMIDE
  • DIMETHYLACETAMIDE
  • N,N-Dimethyl acetamide
  • N,N-DIMETHYL ETHANAMIDE
  • N,N-Dimethylacetamide
  • N,N-DIMETHYLETHANAMIDE
  • N,N-Diméthylacétamide

Noms anglais :

  • N,N-Dimethyl acetamide
  • N,N-Dimethylacetamide
Utilisation et sources d'émission 1 2 3

Le N,N-diméthylacétamide est un excellent solvant pour beaucoup de résines et de polymères, en particulier pour la production de fibres ou de films. Il peut aussi être utilisé en tant que solvant de recristallisation.

Références

  • ▲1.  Kroschwitz, J.I., Kirk-Othmer encyclopedia of chemical technology. 5th ed. Hoboken, N.J. : John Wiley & Sons. (2004-). [RT-423004]
  • ▲1.  Kroschwitz, J.I., Kirk-Othmer encyclopedia of chemical technology. 5th ed. Hoboken, N.J. : John Wiley & Sons. (2004-). [RT-423004]
  • ▲2.  Lewis, R.J., Sr., Hawley's condensed chemical dictionary. 14th ed. New York : John Wiley & Sons. (2001).   http://onlinelibrary.wiley.com/book/10.1002/9780470114735
  • ▲2.  Lewis, R.J., Sr., Hawley's condensed chemical dictionary. 14th ed. New York : John Wiley & Sons. (2001).   http://onlinelibrary.wiley.com/book/10.1002/9780470114735
  • ▲3.  Pohanish, R., Sittig's handbook of toxic and hazardous chemicals and carcinogens. 4ème éd. Norwich (NY) : Noyes Publications. (2002). 2 v.
  • ▲3.  Pohanish, R., Sittig's handbook of toxic and hazardous chemicals and carcinogens. 4ème éd. Norwich (NY) : Noyes Publications. (2002). 2 v.
  • ▲4.  Vincoli, J.W., Risk management for hazardous chemicals : A-F. Vol. 1. Boca Raton : Lewis Publishers. (1997). [RM-515112]
  • ▲5.  Sax's dangerous properties of industrial materials. 11th ed. Hoboken, N.J. : John Wiley & Sons. (2004). [RR-014005]
  • ▲6.  Lewis Sr., R.J., Hazardous chemicals desk reference. 6 éd. Hoboken (New Jersey) : John Wiley & Sons Inc. (2008). [RM-515053]   www.wiley.com
  • ▲7.  Cairelli, S.G., Ludwig, H.R. et Whalen, J.J., Documentation for immediately dangerous to life or health concentrations (IDLHS). Springfield (VA) : NTIS. (1994). PB-94-195047. [RM-515102]   http://www.cdc.gov/niosh/idlh/intridl4.html
  • ▲8.  O'Neil, M.J. et al., The Merck Index : an encyclopedia of chemicals, drugs, & biologicals. 15e éd. Cambridge, G.-B. : Royal Society of Chemistry. (2013). [RM-403001]   https://www.rsc.org/Merck-Index/
  • ▲9.  American Conference of Governmental Industrial Hygienists, «Dimethylacetamide.» In: Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. Cincinnati, Ohio : ACGIH. (2018). Publication #0100Doc.   http://www.acgih.org
  • ▲9.  American Conference of Governmental Industrial Hygienists, «Dimethylacetamide.» In: Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. Cincinnati, Ohio : ACGIH. (2018). Publication #0100Doc.   http://www.acgih.org
  • ▲9.  American Conference of Governmental Industrial Hygienists, «Dimethylacetamide.» In: Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. Cincinnati, Ohio : ACGIH. (2018). Publication #0100Doc.   http://www.acgih.org
  • ▲10.  Handbook of organic industrial solvents. 6th ed. Chicago : Alliance of American Insurers. (1987). [RT-435005]
  • ▲11.  National Fire Protection Association, Fire protection guide to hazardous materials. 14th ed. Quincy, Mass. : NFPA. (2010). [RR-334001]
  • ▲12.  Drolet, D. et Beauchamp, G, Guide d'échantillonnage des contaminants de l'air en milieu de travail. Études et recherches / Guide technique, 8ème éd. revue et mise à jour. Montréal : IRSST. (2012). T-06. [MO-220007]   http://www.irsst.qc.ca
    http://www.irsst.qc.ca/files/documents/PubIRSST/t-06.pdf
  • ▲13.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
  • ▲13.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
  • ▲13.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
  • ▲14.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 6th ed. Cincinnati, Ohio : ACGIH. (1991-2000). Publication 0206. [RM-514008]   http://www.acgih.org
  • ▲15.  Règlement sur la santé et la sécurité du travail [S-2.1, r. 13]. Québec : Éditeur officiel du Québec. [RJ-510071]   http://legisquebec.gouv.qc.ca/fr/ShowDoc/cr/S-2.1,%20r.%2013
  • ▲18.  Bingham, E., Cohrssen, B. et Powell, C.H., Patty's toxicology. A Wiley-Interscience publication. New York (Toronto) : John Wiley. (2001-). [RM-214008]   http://www3.interscience.wiley.com (http://www3.interscience.wiley.com/cgi-bin/mrwhome/104554795/HOME)
  • ▲19.  France. Institut national de recherche et de sécurité, Fiche toxicologique no 261 : N,N-Diméthylacétamide. Cahiers de notes documentaires. Paris : INRS. (2006). [RE-005509]   http://www.inrs.fr/publications/bdd/fichetox.html
    http://www.inrs.fr/publications/bdd/fichetox/fiche.html?refINRS=FICHETOX_261
  • ▲19.  France. Institut national de recherche et de sécurité, Fiche toxicologique no 261 : N,N-Diméthylacétamide. Cahiers de notes documentaires. Paris : INRS. (2006). [RE-005509]   http://www.inrs.fr/publications/bdd/fichetox.html
    http://www.inrs.fr/publications/bdd/fichetox/fiche.html?refINRS=FICHETOX_261
  • ▲20.  OECD, «N,N-DIMETHYLACETAMIDE (DMAC) CAS N°:127-19-5.» In: OECD Screening Information Data Set (SIDS) for High Production Volume Chemicals. Paris : UNEP Publications. (2001).   http://www.inchem.org/documents/sids/sids/127-19-5.pdf
  • ▲20.  OECD, «N,N-DIMETHYLACETAMIDE (DMAC) CAS N°:127-19-5.» In: OECD Screening Information Data Set (SIDS) for High Production Volume Chemicals. Paris : UNEP Publications. (2001).   http://www.inchem.org/documents/sids/sids/127-19-5.pdf
  • ▲21.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
  • ▲22.  Smyth, H.F. et al., «Range-finding toxicity data : List VI.» American Industrial Hygiene Association Journal. Vol. 23, p. 95-107. (1962). [AP-041987]
  • ▲22.  Smyth, H.F. et al., «Range-finding toxicity data : List VI.» American Industrial Hygiene Association Journal. Vol. 23, p. 95-107. (1962). [AP-041987]
  • ▲23.  Initial submission : letter summarizing results from an inhalation developmental toxicity study in rabbits on dimethylacetamide with cover letter . BASF CORP. (1988). Microfiche : OTS0535030, 8EHQ-1291-1933
  • ▲24.  ECHA (European Chemicals Agency) , Information on Chemicals (REACH). Helsinki, Finland.   http://echa.europa.eu/information-on-chemicals/registered-substances
  • ▲24.  ECHA (European Chemicals Agency) , Information on Chemicals (REACH). Helsinki, Finland.   http://echa.europa.eu/information-on-chemicals/registered-substances
  • ▲25.  Solomon, H.M., Ferenz, R.L. et Staples, R.E., «Dimethylacetamide (DMAC) : teratogenic potential and embryo-fetal toxicity by inhalation in the rat.» Teratology. Vol. 29, no. 2, p. 59A. (1984). [AP-031273]
  • ▲26.  Solomon, H.M. et al., «Developmental toxicity of dimethylacetamide by inhalation in the rat .» Fundamental and Applied Toxicology. Vol. 16, no. 3, p. 414-422. (1991). [AP-035116]
  • ▲27.  Thiersch, J.B., «Investigations into the differential effect of compounds on rat litter and mother.» Malformations congénitales des mammifères. , p. 95-113. (1971). [AP-001036]
  • ▲28.  Klimisch, H. J. et Hellwig, J., «Developmental toxicity of dimethylacetamide in rabbits following inhalation exposure.» Human & Experimental Toxicology. Vol. 19, no. 12, p. 676-683. (2000).
  • ▲29.  Johannsen, F. R., Levinskas, G. J. et Schardein, J. L., «Teratogenic response of dimethylacetamide in rats.» Fundamental and applied toxicology. Vol. 9, no. 3, p. 550-556. (1987).
  • ▲30.  Okuda, H. et al., «Developmental toxicity induced by inhalation exposure of pregnant rats to N,N-dimethylacetamide.» Journal of occupational health. Vol. 48, no. 3, p. 154-160. (2006).
  • ▲30.  Okuda, H. et al., «Developmental toxicity induced by inhalation exposure of pregnant rats to N,N-dimethylacetamide.» Journal of occupational health. Vol. 48, no. 3, p. 154-160. (2006).
  • ▲31.  Stula, E.F. et Krauss, W.C., «Embryotoxicity in rats and rabbits from cutaneous application of amide-type solvents and substituted ureas.» Toxicology and applied pharmacology. Vol. 41, no. 1, p. 35-55. (July 1977). [AP-001037]
  • ▲32.  International Agency for Research on Cancer, «Carcinogenicity of some nitrobenzenes and other industrial chemicals..» The Lancet Oncology. Vol. Nov. 1, p. 1-2. (2018).
  • ▲33.  American Conference of Governmental Industrial Hygienists, 2019 TLVs® and BEIs® : threshold limit values for chemical substances and physical agents and biological exposure indices. Cincinnati (OH) : ACGIH. (2019). [NO-003164]   http://www.acgih.org
  • ▲34.  National Institute for Occupational Safety and Health, RTECS (Registry of Toxic Effects of Chemical Substances). Hamilton (Ont) : Canadian Centre for Occupational Health and Safety.   http://ccinfoweb.ccohs.ca/rtecs/search.html
  • ▲34.  National Institute for Occupational Safety and Health, RTECS (Registry of Toxic Effects of Chemical Substances). Hamilton (Ont) : Canadian Centre for Occupational Health and Safety.   http://ccinfoweb.ccohs.ca/rtecs/search.html
  • ▲35.  National Library of Medicine, The Hazardous Substances Data Bank (HSDB). Hamilton (Ont.) : Canadian Centre for Occupational Health and Safety.   http://www.ccohs.ca/
  • ▲36.  Dutch Institute for the Working Environment et Dutch Chemical Industry Association, Chemical safety sheets : working safely with hazardous chemicals. Netherlands : Kluwer Academic Publishers. (1991). [RR-015010]

Autres sources d'information

  • National Institute for Occupational Safety and Health, NIOSH pocket guide to chemical hazards. 3 ed. Cincinnati, Ohio : NIOSH. (2007). [RM-514001]   https://www.cdc.gov/niosh/docs/2005-149/pdfs/2005-149.pdf
  • American Conference of Governmental Industrial Hygienists, 2010 TLVs and BEIs with 7th edition documentation CD-ROM. Cincinnati, OH : ACGIH. (2010). Publication 0111CD. [CD-120061]   http://www.acgih.org
  • Weast, R.C., Astle, M.J. et Beyer, W.H., CRC handbook of chemistry and physics. 69th ed., 1988-1989. Boca Raton (Fla.) : CRC Press. (1988).
  • National Fire Protection Association, Fire protection guide on hazardous materials. 9th ed. Quincy, Mass. : NFPA. (1986).   http://www.nfpa.org/
  • Lenga, R.E., The Sigma-Aldrich library of chemical safety data. 2nd ed. Milwaukee : Sigma-Aldrich. (1988).
  • Windholz, M., The Merck index : an encyclopedia of chemicals, drugs, and biologicals. 10th ed. Rahway ( N.J.) : Merck. (1983). [RM-403001]
  • Dreisbach, R. H., Handbook of poisoning : prevention diagnosis & treatment, 11th ed, Los Altos, Calif. : Lange Medical Publications, 1983 [RM-515008]
  • Smyth, H.F. et al., «Range-finding toxicity data : List VI.» American Industrial Hygiene Association Journal. Vol. 23, p. 95-107. (1962). [AP-041987]
  • FUNDAMENTAL AND APPLIED TOXICOLOGY, VOL. 9, 1987, P. 550-556
  • Bartsch, W. et al., «Acute toxicity of various solvents in the mouse and rat.» Drug Research. Vol. 26, no. 8, p. 1581-1583. (1976). [AP-029722]
  • Kennedy, G.L. , «Subchronic inhalation toxicity of dimethylacetamide in rats.» Toxicologist . Vol. 4, p. 65. (1984). [AP-031274]
  • «The influence of solvent on the teratogenic effect of folic acid antagonist in the rat.» Experimental and Molecular Pathology . Vol. 5, p. 134-145. (1966). [AP-031275]
  • Fundamental and Applied Toxicology, VOL. 7, 1986, P. 132-137
  • Taft, R.W. et al., «Solubility properties in polymers and biological media 5 : an analysis of the physicochemical properties wich influence + octanol-water partition coefficients of aliphatic and aromatic solutes.» Journal of Pharmaceutical Sciences. Vol. 74, no. 8, p. 807-814. (1985). [AP-012173]
  • Wang, G.M., Kier, L.D. et Pounds, G.W., «Male fertility study on N,N-dimethylacetamide administered by the inhalation route to Sprague-Dawley rats.» Journal of Toxicology and Environmental Health. Vol. 27, no. 3, p. 297-305. (1989). [AP-027389]
  • Miller, W.L., Frank, D.W. et Sutton, M.J., «Antifertility activity of NDA in hamsters : protection with a luteotropic complex.» Proceedings of the Society for Experimental Biology and Medicine. Vol. 166, p. 199-204. (1981). [AP-016431]
  • Material safety data sheets / Genium's Handbook of safety, health, and environmental data. Genium Publishing Corp. (1999-).   http://www.genium.com/hazmat/
  • National Institute for Occupational Safety and Health et États-Unis. Occupational Safety and Health Administration, Occupational health guidelines for chemical hazards. Vol. 1. Cincinnati : Centers for Disease Control. (1981-). DHSS-NIOSH 81-123. [RR-015002]   http://www.cdc.gov/niosh/docs/81-123/
  • Shepard, T.H., Catalog of teratogenic agents. 6th ed. London : John Hopkins University Press. (1989).
  • McGregor, D.B., Tier ii mutagenic screening of 13 NIOSH priority compounds individual compound. Report, n,n-dimethyl-lacetamide, report no. 27. Musseburg. (1980). Microfiche : PB83-149732, NIOSH-210-78-0026(3)

La cote entre [ ] provient de la banque Information SST du Centre de documentation de la CNESST.