Identification

Description


Formule moléculaire brute : C23H36N4O10S2

Principaux synonymes

Noms français :

  • 4,4'-DIAMIDINO-ALPHA,OMEGA-DIPHENOXYPENTANE ISETHIONATE
  • 4,4'-DIAMIDINOPHENOXYPENTANE DI(BETA-HYDROXYETHANESULFONATE)
  • BENZAMIDINE, 4,4'-(PENTAMETHYLENEDIOXY)DI-, BIS(BETA-HYDROXYETHANESULFONATE)
  • COMPOSE DE L'ACIDE HYDROXY-2 ETHANESULFONIQUE ET DE BIS((OXY)BIS-PENTANEDIYL-1,5)(BENZENCARBOXIMIDAMIDE) (2:1)
  • COMPOSE DE L'ACIDE HYDROXY-2 ETHANSULFONIQUE ET DE (PENTAMETHYLENEDIOXY)-4,4' DIBENZAMIDINE (2:1)
  • DIAMIDINOPHENOXYPENTANE-4,4' DI(HIDROXY-BETA ETHANESULFONATE)
  • ETHANESULFONIC ACID, 2-HYDROXY-, COMPD. WITH 4,4'-(1,5-PENTANEDIYLBIS(OXY))BIS(BENZENECARBOXIMIDAMIDE) (2:1)
  • ETHANESULFONIC ACID, 2-HYDROXY-, COMPD. WITH 4,4'-(PENTAMETHYLENEDIOXY)DIBENZAMIDINE (2:1)
  • ISETHIONATE DE BIS(P-AMIDINOPHENOXY)-1,5 PENTANE
  • ISETHIONATE DE PENTAMIDINE
  • Iséthionate de pentamidine
  • P,P'-(PENTAMETHYLENEDIOXY)DIBENZAMIDINE BIS(BETA-HYDROXYMETHANESULFONATE)
  • PENTAMIDINE, ISETHIONATE DE

Noms anglais :

  • 4,4-(PENTAMETHYLENEDIOXY)DIBENZAMINE ISETHIONATE
  • LOMIDINE ISETHIONATE
  • PENTAMIDINE DI-ISETHIONATE
  • PENTAMIDINE DIISETHIONATE
  • Pentamidine isethionate
  • PENTAMIDINE ISOTHIONATE
Utilisation et sources d'émission

Médicament (antibiotique)

Références

  • ▲1.  Schardein, J.L., Chemically induced birth defects. 3ème rév. & expanded. New York : Dekker. (2000). [MO-122294]
  • ▲2.  Fortunato, S.J. et Bawdon, R.E., «Determination of pentamidine transfer in the in vitro perfused human cotyledon with high-performance liquid chromatography.» American Journal of Obstetrics and Gynecology. Vol. 160, no. 3, p. 759-761. (1989). [AP-046748]
  • ▲3.  Waxman, S., Corcino, J.J. et Herbert, V., «Drugs, toxins and dietary amino acids affecting vitamin B12 or folic acid absorption or utilization.» The American Journal of Medicine. Vol. 48, p. 599-608. (1970).
  • ▲4.  Rhone-Poulenc Pharma Inc., Monographie du Pentacarinat (iséthionate de pentamidine). (1993).
  • ▲5.  Harstad, T.W. et al., «Embryofetal effects of pentamidine isethionate administered to pregnant Sprague-Dawley rats.» American Journal of Obstetrics and Gynecology. Vol. 163, no. 3, p. 912-916. (1990). [AP-032718]
  • ▲6.  Coustan, D.R. et Mochizuki, T.K., Handbook for prescribing medications during pregnancy. 3rd ed. New York : Lippincott-Raven. (1998). [RM-015024]
  • ▲7.  Briggs, G.G., Freeman, R.K. et Yaffe, S.J., Drugs in pregnancy and lactation : a reference guide to fetal and neonatal risk. 5ème éd. Baltimore : Williams & Wilkins. (1998).
  • ▲8.  Ito, S. et Koren, G., «Estimation of fetal risk from aerosolized pentamidine in pregnant healthcare workers.» Chest. Vol. 106, no. 5, p. 1460-1462. (1994).
  • ▲9.  Audebert, M., Le Parco, J.-C. et Gendre, J.-P., «Absorption des folates : physiopathologie et pathologie.» Gastroenterol. Clin. Biol.C. Vol. 2, p. 309-320. (1978).
  • ▲10.  Manda, D. et al., «Pentamidine prophylaxis in pregnancy.» American Journal of Obstetrics and Gynecology. Vol. 166, no. 1(partie2), p. 387. (1992).
  • ▲11.  Conover, B. et al., «Aerosolized pentamidine and pregnancy.» Annals of International Medicine. Vol. 109, no. 11, p. 927. (1988). [AP-024999]
  • ▲12.  Schwebke, K. et al., «Pentamidine concentrations in a mother with AIDS and in her neonate.» Clinical Infectious Diseases. Vol. 20, p. 1569-1570. (1995).
  • ▲13.  Connor, Th. H. et Trizna, Z., «Pentamidine isethionate is negative in tests for microbial mutagenicity and chromosomal breakage in vitro.» Toxicology Letters. Vol. 63, p. 69-74. (1992). [AP-047352]
  • ▲14.  Berger, B.J. et al., «Metabolic N-hydroxylation of pentamidine in vitro.» Antimicrobial nAgents and Chemotherapy. Vol. 34, no. 9, p. 1678-2684. (1990).
  • ▲15.  Stauffert, I. et al., «Investigations on mutagenicity and genotoxicity of pentamidine and some related trypanocidal diamines.» Mutation Research. Vol. 245, p. 93-98. (1990).

Autres sources d'information

  • Sax, N.I., Dangerous properties of industrial materials. 7th ed. Toronto : Van Nostrand Reinhold. (1989). [RR-014005]
  • Budavari, S. et O'Neil, M., The Merck index : an encyclopedia of chemicals, drugs, and biologicals. 11th ed. Rahway ( N.J.) : Merck. (1989). [RM-403001]
  • Rhone-Poulenc Pharma Inc., Monographie du Pentacarinat (iséthionate de pentamidine). (1993).
  • ANNALS OF INTERNAL MEDICINE, VOL.109, NO.11, 1988, P.927 [AP-024999]
  • ANTIBIOTICS AND CHEMOTHERAPY, VOL.11, NO.11, 1952, P.581-589 [AP-037372]
  • CHEST, VOL.100, NO.4, 1991, P.1177 [AP-037376]
  • THE LANCET, VOL.1, NO.8649, 1989, P.1271-1272 [AP-037377]
  • LA PRESSE MEDICALE, VOL.21, NO.3, 1992, P.130-131 [AP-040113]
  • ANNALS OF INTERNAL MEDICINE, VOL.110, NO.2, 1989, P.1035-1036 [AP-040114]
  • INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, VOL.12, NO.6, 1991, P.375-382 [AP-040117]
  • CONTACT DERMATITIS, VOL.29, 1993, P.158-159 [AP-040855]

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