WHMIS (1,2-epoxybutane)

Workplace Hazardous Materials Information System

WHMIS 2015 classification - Note to reader

• Flammable liquids - Category 21
• Flash point = -22 °C closed cup (non reported method) and boiling point = 63 °C

• Acute toxicity - oral - Category 42 3 4

• Acute toxicity - dermal - Category 42 3 4 5

• Acute toxicity - inhalation - Category 42 4 5

• Skin corrosion/irritation - Category 12 4

• Serious eye damage/eye irritation - Category 12

• Carcinogenicity - Category 22

• Physical hazards not otherwise classified (exploding bomb) - Category 11 6 7

• Health hazards not otherwise classified (corrosion) - Category 1

Danger

Highly flammable liquid and vapour (H225)
Harmful if swallowed (H302)
Harmful in contact with skin (H312)
Harmful if inhaled (H332)
Causes severe skin burns and eye damage (H314)
Suspected of causing cancer (H351)
Undergoes vigorous reaction of decomposition or polymerization
Causes severe damage to the respiratory tract

Ingredient disclosure

Comments: Available data indicate that the LC50 of 1,2-epoxybutane is between 6,05 mg/L/4h and 19,32 mg/L/4h (vapors). Inhalation acute toxicity (H332) classification was established with 19,32 mg/L/4h.

References

• ▲1.  National Fire Protection Association, Fire protection guide to hazardous materials. 14th ed. Quincy, Mass. : NFPA. (2010). [RR-334001]
• ▲2.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
• ▲3.  Bingham, E., Cohrssen, B. et Powell, C.H., Patty's toxicology. A Wiley-Interscience publication. New York (Toronto) : John Wiley. (2001-). [RM-214008]   http://www3.interscience.wiley.com (http://www3.interscience.wiley.com/cgi-bin/mrwhome/104554795/HOME)
• ▲4.  OECD SIDS, «1,2-Epoxubutane CAS N°.: 106-88-7.» In: SIDS Initial assessment Report for 11th SIAM. , p. 1-63. Orlando. (2001).   http://www.inchem.org/documents/sids/sids/106887.pdf
• ▲5.  National Institute for Occupational Safety and Health, RTECS (Registry of Toxic Effects of Chemical Substances). Hamilton (Ont) : Canadian Centre for Occupational Health and Safety.   http://ccinfoweb.ccohs.ca/rtecs/search.html
• ▲6.  United States. National Ocean Service. Office of Response and Restoration., Computer aided management of emergency operations chemicals (CAMEO chemicals) : online database of hazardous materials. USA : National Oceanic and Atmospheric Administration.   http://cameochemicals.noaa.gov/search/simple
  http://cameochemicals.noaa.gov/
• ▲7.  Pohanish, R.P. et Greene, S.A., Wiley guide to chemical incompatibilities. 3ème éd. New Jersey : John Wiley & Sons Inc. (2009). [RR-015033]   www.wiley.com

The [number] refers to the Information SST database of the CNESST Documentation Center.