CAS Number : 304-20-1

The information for this substance is partially available.

The section entitled Complete data sheet is not available in English for this substance. Consult the French version.

Identification

Description


Formule moléculaire brute : C8H9CLN4

Principaux synonymes

Noms français :

  • Chlorhydrate d'hydralazine

Noms anglais :

  • 1(2H)-PHTHALAZINONE, HYDRAZONE, MONOHYDROCHLORIDE
  • Hydralazine hydrochloride
  • HYDRALAZINE MONOHYDROCHLORIDE
  • PHTHALAZINONE, HYDRAZONE, MONOHYDROCHLORIDE

Références

  • ▲1.  Kligman, A.M., «The identification of contact allergens by human assay. III. The maximization test : a procedure for screening and rating contact sensitizers.» Journal of Investigative Dermatology. Vol. 47, no. 5, p. 393-409. (1966). [AP-022756]
  • ▲2.  Mayer, R.L., Eisman, P.C. et Jaconia, D., «Experimental sensitization of guinea-pigs to 1-hydrazinophthalazine; with discussion of the use of guinea-pigs for the forecast of clinical sensitizations.» Journal of Investigative Dermatology. Vol. 24, p. 281-291. (1955).
  • ▲3.  Katsutani, N. et Shionoya, H., «Drug-specific immune responses induced by immunization with drugs in guinea pigs and mice.» Journal of Toxicological Sciences. Vol. 17, no. 4, p. 169-183. (1992).
  • ▲4.  Kligman, A.M. et Magnusson, B., «The identification of contact allergens by animal assay : the guinea pig maximization test.» Journal of investigative dermatology. Vol. 52, no. 3, p. 268-276. (1969).   http://www.nature.com/jid/journal/v52/n3/pdf/jid196942a.pdf
  • ▲5.  van Ketel, W.G., «Contact dermatitis from a hydrazine-derivate in a stain remover. Cross sensitization to apresoline and isoniazid.» Acta Dermato-Venereologica. Vol. 44, p. 49-53. (1964). [AP-033591]
  • ▲6.  IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, Overall evaluations of carcinogenicity : an updating of IARC monographs volumes 1-42. IARC monographs on the evaluation of carcinogenic risks to humans, Supplement 7. Lyon : International Agency for Research on Cancer. (1987).   https://monographs.iarc.fr/wp-content/uploads/2018/06/Suppl7.pdf
    http://monographs.iarc.fr/
  • ▲7.  IARC Working Group on the Evaluation of Carcinogenic Risks of Chemical to Humans, Some pharmaceutical drugs. IARC monographs on the evaluation of the carcinogenic risk, Vol. 24. Lyon : International Agency for Research on Cancer. (1980).   https://monographs.iarc.fr/wp-content/uploads/2018/06/mono24.pdf
    http://www.iarc.fr

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