Hexahydrophthalic acid anhydride

CAS Number : 85-42-7

  • Complete data sheet (Available in French only)
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  • Summary

The information for this substance is partially available.

The section entitled Complete data sheet is not available in English for this substance. Consult the French version.



Formule moléculaire brute : C8H10O3

Principaux synonymes

Noms français :

  • Anhydride hexahydrophtalique

Noms anglais :

  • Hexahydrophthalic acid anhydride
  • Hexahydrophthalic anhydride
  • Hexahydrophthalic anhydride (HHPA)
  • Hexahydrophthalic anhydride, all isomers [85-42-7]


  • ▲1.  Rosenberg, N., Rousselin, X. et Gervais, P., «Fiche d'allergologie respiratoire no. 10. Allergie respiratoire professionnelle aux anhydrides d'acide.» Documents pour le Médecin du Travail. Vol. 35, p. 271-276. (1988). [AP-023601]   http://www.dmt-prevention.fr/
  • ▲2.  Venables, K.M., «Low molecular weight chemicals, hypersensitivity, and direct toxicity: the acid anhydrides.» British Journal of Industrial Medicine. Vol. 46, p. 222-232. (1989). [AP-025649]
  • ▲3.  Rosenman, K.D. et al., «Occupational asthma caused by himic anhydride.» Scandinavian Journal of Work, Environment & Health. Vol. 13, p. 150-154. (1987).
  • ▲4.  Zeiss, C.R., «Reactive chemicals in industrial asthma.» Journal of Allergy and Clinical Immunology. Vol. 87, no. 4, p. 755-761. (1991).
  • ▲5.  Yokota, K., Johyama, Y. et Yamaguchi, K., «A cross-sectional survey of 32 workers exposed to hexahydrophthalic and methylhexahydrophthalic anhydrides.» Industrial Health. Vol. 40, no. 1, p. 36-41. (2002).
  • ▲6.  Nielsen, J. et al., «Nasal challenge shows pathogenetic relevance of specific IgE serum antibodies for nasal symptoms caused by hexahydophthalic anhydride.» Clinical and Experimental Allergy. Vol. 24, no. 5, p. 440-449. (1994).
  • ▲7.  Kanerva, L. et al., «Airborne allergic contact urticaria from methylhexahydrophthalic anhydride and hexahydrophthalic anhdride.» Contact Dermatitis. Vol. 41, no. 6, p. 339-341. (1999).
  • ▲8.  Schöeneich, R. et Wallenstein, G., «Anhydrides of dicarboxylic acids as occupational allergens : respiratory diseases induced by hexahydrophthalic anhydride as component of epoxy resin.» Allergologie. Vol. 14, no. 9, p. 372-375. (1991).
  • ▲9.  Nielsen, J. et al., «Exposure to hexahydrophthalic and methylhexahydrophthalic anhydrides - dose-response for sensitization and airway effects.» Scandinavian Journal of Work, Environment & Health. Vol. 27, no. 5, p. 327-334. (2001).
  • ▲10.  Moller, D.R. et al., «Detection of IgE-mediated respiratory sensitization in workers exposed to hexahydrophthalic anhydride.» Journal of Allergy and Clinical Immunology. Vol. 75, no. 6, p. 663-672. (1985).
  • ▲11.  Bernstein, D.I. et al., «Heterogeneity of specific-IgE responses in workers sensitized to acid anhydride compounds .» Journal of Allergy and Clinical Immunology. Vol. 74, no. 6, p. 794-801. (1984). [AP-005837]
  • ▲12.  Rosenberg, N. et al., «Réaction immunologique croisée aux anhydrides d'acides. Intérêt pratique. À propos de trois cas.» Archives des maladies professionnelles, de médecine du travail et de sécurité sociale. Vol. 50, no. 5, p. 459-461. (1989). [AP-053317]
  • ▲13.  Chee, C.B.E. et al., «Occupational asthma due to hexahydrophthalic anhydride: a case report.» British Journal of Industrial Medicine. Vol. 48, p. 643-645. (1991).
  • ▲14.  Welinder, H. et al., «Exposure-response relationships in the formation of specific antibodies to hexahydrophthalic anhydride in exposed workers.» Scandinavian Journal of Work, Environment & Health. Vol. 20, p. 459-465. (1994).
  • ▲15.  Grammer, L.C. et al., «Risk factors for immunologically mediated respiratory disease from hexahydrophthalic anhydride.» Journal of Occupational Medicine. Vol. 36, no. 6, p. 642-646. (1994).
  • ▲16.  Drexler, H. et al., «Detection and clinical relevance of a type I allergy with occupational exposure to hexahyrophthalic anhydride and methyltetrahydrophthalic anhydride.» International Archives of Occupational and Environmental Health. Vol. 65, p. 279-283. (1994).
  • ▲17.  Welinder, H. et Nielsen, J., «Immunologic tests of specific antibodies to organic acid anhydrides.» Allergy. Vol. 46, p. 601-609. (1991). [AP-036844]
  • ▲18.  Règlement sur la santé et la sécurité du travail [S-2.1, r. 13]. Québec : Éditeur officiel du Québec. [RJ-510071]   http://legisquebec.gouv.qc.ca/fr/ShowDoc/cr/S-2.1,%20r.%2013

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