alpha-Chloroacétophénone

Numéro CAS : 532-27-4

Identification

Description


Numéro UN : UN1697

Formule moléculaire brute : C8H7ClO

Principaux synonymes

Noms français :

  • alpha-Chloroacetophenone
  • alpha-Chloroacétophénone
  • CHLORO-2 PHENYL-1 ETHANONE
  • CHLOROACETOPHENONE (ALPHA-)
  • Chloroacétophénone
  • CHLOROMETHYL PHENYL KETONE
  • CHLORURE DE PHENACYLE
  • ETHANONE, 2-CHLORO-1-PHENYL-
  • GAZ CAP
  • GAZ LACRYMOGENE CN
  • GAZ LACRYMOGENE CP
  • OMEGA-CHLOROACETOPHENONE
  • PHENYL CHLORO METHYL CETONE
  • PHENYL CHLORO METHYL KETONE
  • PHENYL CHLOROMETHYL CETONE

Noms anglais :

  • 1-CHLOROACETOPHENONE
  • 2-Chloroacetophenone
  • alpha-Chloroacetophenone
  • CAP GAS
  • Chloroacetophenone
  • CHLOROACETOPHENONE (APLHA-)
  • CN GAS
  • Phenacyl chloride
  • PHENYLCHLOROMETHYLKETONE
Utilisation et sources d'émission

Fabrication de produits pharmaceutiques, agent lacrymogène

Références

  • ▲1.  Cairelli, S.G., Ludwig, H.R. et Whalen, J.J., Documentation for immediately dangerous to life or health concentrations (IDLHS). Springfield (VA) : NTIS. (1994). PB-94-195047. [RM-515102]   http://www.cdc.gov/niosh/idlh/intridl4.html
  • ▲2.  Drolet, D. et Beauchamp, G, Guide d'échantillonnage des contaminants de l'air en milieu de travail. Études et recherches / Guide technique, 8ème éd. revue et mise à jour. Montréal : IRSST. (2012). T-06. [MO-220007]   http://www.irsst.qc.ca
    http://www.irsst.qc.ca/files/documents/PubIRSST/t-06.pdf
  • ▲6.  Fuchs, V.T. et Ippen, H., «Kontaktallergie auf CN- und CS-tränengas.» Dermatosen in Beruf und Umwelt. Vol. 34, no. 1, p. 12-14. (1986). [AP-013596]
  • ▲7.  Kanerva, L. et al., «A single accidental exposure may result in a chemical burn, primary sensitization and allergic contact dermatitis.» Contact Dermatitis. Vol. 31, p. 229-235. (1994).
  • ▲8.  Fisher, A.A., «Dermatitis due to tear gases (lacrimators).» International Journal of Dermatology. Vol. 9, no. 2, p. 91-95. (1970).
  • ▲9.  Pfeiff, B., «Contact dermatitis due to chloroacetophenone (tear gas).» Z. Hautkr. Vol. 60, no. 1-2, p. 178-180, 183-184. (1985).
  • ▲10.  Rothberg, S., «Skin sensitization potential of the riot control agents BBC, DM, CN and CS in guinea pigs.» Military Medicine. Vol. 135, no. 7, p. 552-556. (1970). [AP-062514]
  • ▲11.  Brand, C.U. et al., «Lymphocyte stimulation test, a possible alternative for verifying chloroacetophenone sensitization.» Hautarzt. Vol. 46, no. 10, p. 702-704. (1995).
  • ▲12.  Horn, T. et Mulders, A., «Contact dermatitis caused by 2-chloroacetophenone after tear gas exposure.» Der Hautarzt. Vol. 37, no. 5, p. 287-289. (1986).
  • ▲13.  Leenutaphong, V. et Goerz, G., «Allergic contact dermatitis from chloroacetophenone (tear gas).» Contact Dermatitis . Vol. 20, p. 316. (1989).
  • ▲14.  Frazier, C.A., «Contact allergy to mace.» JAMA : the Journal of the American Medical Association. Vol. 236, no. 22, p. 2556. (1976).
  • ▲15.  Penneys, N.S., Israel, R.M. et Indgin, S.M., «Contact dermatitis due to 1-chloroacetophenone and chemical mace.» New England Journal of Medicine. Vol. 281, no. 8, p. 413-415. (1969). [AP-021026]
  • ▲16.  Madden, J.F., «Cutaneous hypersensitivity to tear gas (chloroacetophenone).» Archives of Dermatology and Syphilology. Vol. 63, p. 133-134. (1951). [AP-021030]
  • ▲17.  Penneys, N.S., «Contact dermatitis to chloroacetophenone.» Federation Proceedings. Vol. 30, no. 1, p. 96-99. (1971). [AP-021033]
  • ▲18.  Queen, F.B. et Stander, T. , «Allergic dermatitis following exposure to tear gas (chloroacetophenone, CN).» JAMA : The Journal of the American Medical Association. Vol. 117, no. 22, p. 1879. (1941). [AP-021028]
  • ▲19.  Maibach, H.I. et Marzulli, F.N., «Allergic sensitization potential of riot control lacrimants: human Draize test.» FDA by-lines. Vol. 4, p. 189. (1971). [AP-023924]
  • ▲20.  Chung, C.W. et Giles, A.L., «Sensitization of guinea pigs to alpha-chloroacetophenone (CN) and ortho-chlorobenzylidenemalonitrile (CS), tear gas chemicals.» Journal of Immunology. Vol. 109, no. 2, p. 284-293. (1972). [AP-021032]
  • ▲21.  Canada. Ministère des transports, Règlement sur le transport des marchandises dangereuses. Ottawa : Éditions du gouvernement du Canada. (2014). [RJ-410222]   http://www.tc.gc.ca/fra/tmd/clair-menu-497.htm
    http://www.tc.gc.ca/tmd/menu.htm
  • ▲22.  Ballantyne, B. et Swanston, D.W., «The comparative acute mammalian toxicity of 1-chloroacetophenone (CN) and 2-chlorobenzylidene malonitrile.» Archives of Toxicology. Vol. 40, p. 75-95. (1978). [AP-022346]
  • ▲23.  Holland, P. et White, R.G., «The cutaneous reactions produced by o-chlorobenzylidenemalonitrile and w-chloroacetophenone when applied directly to the skin of human subjects.» British Journal of Dermatology. Vol. 86, p. 150-154. (1972). [AP-062510]
  • ▲24.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
  • ▲25.  Deichmann, W.B. et al., «Observations on the effects of diphenyl, o- and p-aminodiphenyl, o- and p-nitrodiphenyl and dihydroxyoctachlorodiphenyl upon experimental animals.» Journal of Industrial Hygiene and Toxicology. Vol. 20, no. 1, p. 1-13. (1947). [AP-021167]
  • ▲26.  Pohanish, R.P. et Greene, S.A., Wiley guide to chemical incompatibilities. 3ème éd. New Jersey : John Wiley & Sons Inc. (2009). [RR-015033]   www.wiley.com
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Autres sources d'information

  • National Institute for Occupational Safety and Health, NIOSH pocket guide to chemical hazards. Washington, D.C. : U.S. G.P.O. (1985). [RM-514001]
  • American Conference of Governmental Industrial Hygienists, 2010 TLVs and BEIs with 7th edition documentation CD-ROM. Cincinnati, OH : ACGIH. (2010). Publication 0111CD. [CD-120061]   http://www.acgih.org
  • Weiss, G., Hazardous Chemicals Data Book. 2nd ed. Park Ridge, N.J. : Noyes Data Corporation. (1986). [RR-015005]
  • Lenga, R.E., The Sigma-Aldrich library of chemical safety data. 2nd ed. Milwaukee : Sigma-Aldrich. (1988).
  • Grant, W.M., Toxicology of the eye : effects on the eyes and visual systems from chemicals, drugs, metals and minerals, plants, toxins and venoms; also, systemic side effects from eye medications. 3rd. ed. Springfield (ILL) : Charles C. Thomas. (1986). [RM-515030]
  • Windholz, M., The Merck index : an encyclopedia of chemicals, drugs, and biologicals. 10th ed. Rahway ( N.J.) : Merck. (1983). [RM-403001]
  • Proctor, N.H. et Hughes, J.P., Chemical hazards of the workplace. Toronto : J.B. Lippincott. (1978). [RM-214010]
  • Canutec. Guide de premières mesures d'urgence. Ottawa : Centre d'Édition du Gouvernement du Canada. (1986).
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  • UNITED STATES FOOD AND DRUG ADMINISTRATION BY-LINES, VOL. 1, NO 4, 1971, P. 188
  • Kappas, A. et al., «Genotoxicity studies on the organophosphorus insecticide chloroacetophenone.» Mutation Research. Vol. 240, no. 3, p. 203-208. (1990). [AP-028080]
  • Punte, C.L. et al., «Inhalation studies with chloroacetophenone, diphenylaminochloroarsine and pelargonic morpholide - II. human exposures.» American Industrial Hygiene Association Journal. Vol. 23, p. 199-202. (1962). [AP-022345]
  • Gaskins, J.R. et al., «Lacrimating agents (CS and CN) in rats and rabbits.» Archives of Environmental Health. Vol. 24, p. 449-454. (1972). [AP-020031]
  • Gwynn, R.H. et Salaman, M.H., «Studies on co-carcinogenesis SH-reactors and other substances tested for co-carcinogenic action in mouse skin.» British Journal of Cancer. Vol. 7, p. 482-489. (1953). [AP-022347]
  • Ingram, J.T. , «Dermatitis from exposure to tear gas.» British Journal of Dermatology. Vol. 54, p. 319-321. (1942). [AP-021029]
  • National Institute for Occupational Safety and Health et États-Unis. Occupational Safety and Health Administration, Occupational health guidelines for chemical hazards. Vol. 1. Cincinnati : Centers for Disease Control. (1981-). DHSS-NIOSH 81-123. [RR-015002]   http://www.cdc.gov/niosh/docs/81-123/
  • Sittig, M., Handbook of toxic and hazardous chemicals. 2ème éd. Park Ridge ( N.J.) : Noyes Publications. (1985). [RR-015003]

La cote entre [ ] provient de la banque ISST du Centre de documentation de la CSST.