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L'information disponible sur cette substance est partielle. Pour de plus amples renseignements, veuillez communiquer avec le Répertoire toxicologique.

Identification

Description


Numéro UN : UN2579

Formule moléculaire brute : C4H10N2

Principaux synonymes

Noms français :

  • 1,4-DIAZACYCLOHEXANE
  • 1,4-DIETHYLENEDIAMINE
  • 1,4-PIPERAZINE
  • DIAZA-1,4 CYCLOHEXANE
  • DIETHYLENE-1,4 DIAMINE
  • DIETHYLENEDIAMINE
  • DIETHYLENEIMINE
  • Diéthylènediamine
  • HEXAHYDRO-1,4-DIAZINE
  • N,N-DIETHYLENE DIAMINE
  • N,N-DIETHYLENEDIAMINE
  • Pipérazine

Noms anglais :

  • HEXAHYDROPYRAZINE
  • PIPERAZIDINE
  • Piperazine
  • Piperazine and salts, as piperazine
  • PIPERAZINE ANHYDROUS
  • PIPERAZINE, ANHYDROUS
  • PYRAZINE HEXAHYDRIDE
  • PYRAZINE, HEXAHYDRO-
Utilisation et sources d'émission

Fabrication de produits pharmaceutiques, insecticide

Références

  • ▲1.  Lewis, R.J., Sr., Hawley's condensed chemical dictionary. 14th ed. New York : John Wiley & Sons. (2001). [RS-407001]
  • ▲2.  Pohanish, R.P., Sittig's handbook of toxic and hazardous chemicals and carcinogens. Vol. 2, 6ème éd. Amsterdam : William Andrew. (2012). [RR-015003]   http://www.sciencedirect.com/science/book/9781437778694
  • ▲6.  Welinder, H., Hagmar, L. et Gustavsson, C., «IgE antibodies against piperazine and N-methyl-piperazine in two asthmatic subjects.» International Archives of Allergy and Applied Immunology. Vol. 79, no. 3, p. 259-262. (1986). [AP-061816]
  • ▲7.  Hagmar, L. et al., «Small airways function in workers exposed to piperazine.» International Archives of Occupational and Environmental Health. Vol. 59, p. 521-528. (1987).
  • ▲8.  Hagmar, L. et al., «Piperazine-induced occupational asthma.» Journal of Occupational Medicine. Vol. 24, no. 3, p. 193-197. (1982).
  • ▲9.  Hagmar, L. et al., «Piperazine-induced airway symptoms: exposure-response relationships and selection in an occupational setting.» American Journal of Industrial Medicine. Vol. 6, p. 347-357. (1984).
  • ▲10.  Hagmar, L. et Welinder, H., «Prevalence of specificIgE antibodies against piperazine in employees of a chemical plant.» International Archives of Allergy and Applied Immunology. Vol. 81, no. 1, p. 12-16. (1986).
  • ▲11.  Graham, C., Rosenkranz, H.S. et Karol, M.H., «Structure-activity model of chemicals that cause human respiratory sensitization.» Regulatory Toxicology and Pharmacology. Vol. 26, p. 296-306. (1997).
  • ▲12.  Fregert, S., «Respiratory symptoms with piperazine patch testing.» Contact Dermatitis. Vol. 2, p. 61-62. (1976). [AP-061826]
  • ▲13.  Rudzki, E., Rebandel, P. et Grzywa, Z., «Contact allergy in the pharmaceutical industry.» Contact Dermatitis. Vol. 21, p. 121-122. (1989).
  • ▲14.  Calnan, C.D., «Occupational piperazine dermatitis.» Contact Dermatitis. Vol. 1, p. 126. (1975). [AP-019319]
  • ▲15.  Asthmagen? : critical assessments of the evidence for agents implicated in occupational asthma. Health and Safety Executive. Sudbury, Suffolk, G.B. : HSE Books. (2001). [MO-020018]   http://www.hse.gov.uk/asthma/asthmagen.pdf
  • ▲16.  Leung H.W. et Auletta C.S., «Evaluation of skin sensitization and cross-reaction of nine alkyleneamines in the guinea pig maximization test.» Journal of toxicology. Cutaneous and ocular toxicology. Vol. 16, no. 3, p. 189-195. (1997). [AP-053750]
  • ▲17.  Canada. Ministère des transports, Règlement sur le transport des marchandises dangereuses. Ottawa : Éditions du gouvernement du Canada. (2014). [RJ-410222]   http://www.tc.gc.ca/fra/tmd/clair-menu-497.htm
    http://www.tc.gc.ca/tmd/menu.htm

Autres sources d'information

  • Lide, D.R. , CRC handbook of chemistry and physics. 73rd ed. Boca Raton, Fla : CRC Press. (1992). [RS-014001]
  • Mark, H.F., Grayson, M. et Eckroth, D., Kirk-Othmer encyclopedia of chemical technology. 3rd ed. New York : Wiley. (1978-84). [RT-423004]
  • Lewis, R.J., Sax's dangerous properties of industrial materials. Vol. 1, 8ème éd. New York : Van Nostrand Reinhold. (1992). [RR-014005]
  • National Fire Protection Association, Fire protection guide on hazardous materials. 10th ed. Quincy, Mass. : NFPA. (1991). [RR-334001]   http://www.nfpa.org/
  • Lenga, R.E. et Votoupal, K.L., The Sigma-Aldrich library of regulatory and safety data. Vol. 1. Milwaukee : Sigma-Aldrich. (1993). [RM-515040]
  • Patty, F.A., Patty's industrial hygiene and toxicology. Vol. 2, 3rd ed. New York : John Wiley & Son. (1978).
  • Budavari, S. et O'Neil, M., The Merck index : an encyclopedia of chemicals, drugs, and biologicals. 11th ed. Rahway ( N.J.) : Merck. (1989). [RM-403001]
  • MSDS. PIPERAZINE, AKZO CHEMICALS LTD., 1991

La cote entre [ ] provient de la banque ISST du Centre de documentation de la CSST.