WHMIS (1,2-Benzisothiazolone)

Workplace Hazardous Materials Information System

WHMIS 1988 classification - Note to reader

• 

  D2B

Disclosure at 1,0% according to classification criteria

WHMIS 2015 classification - Note to reader

• Acute toxicity - oral - Category 44

• Skin corrosion/irritation - Category 25 6 7 8

• Serious eye damage/eye irritation - Category 16

• Skin sensitization - Category 11 2 3 5 6 9

• Combustible dusts - See comments below5

Danger

Harmful if swallowed (H302)
Causes skin irritation (H315)
Causes serious eye damage (H318)
May cause allergic skin reaction (H317)

Comments: This product could belong to the hazard class "Combustible dust", based on various factors related to the combustibility and explosiveness of its dust, including composition, shape and size of the particles.

References

• ▲1.  Roberts, D.L., Messenger, A.G. et Summerly, R., «Occupational dermatitis due to 1,2-benzisothiazolin-3-one in the pottery industry.» Contact Dermatitis. Vol. 7, p. 145-147. (1981). [AP-041288]
• ▲2.  Sanz-Gallen, P. et al., «Allergic contact due to 1,2-benzothiazolin-3-one in paint manufacture.» Contact Dermatitis. Vol. 27, p. 271-272. (1992). [AP-041291]
• ▲3.  Freeman, S., «Allergic contact dermatitis due to 1,2-benzisothiazolin-3-one in gum arabic.» Contact Dermatitis. Vol. 11, p. 146-149. (1984).
• ▲4.  National Institute for Occupational Safety and Health, RTECS (Registry of Toxic Effects of Chemical Substances). Hamilton (Ont) : Canadian Centre for Occupational Health and Safety.   http://ccinfoweb.ccohs.ca/rtecs/search.html
• ▲5.  France. Institut national de recherche et de sécurité, Fiche toxicologique no 243 : 1,2-Benzisothiazol-3(2H)-one. Cahiers de notes documentaires. Paris : INRS. (2002). [RE-005509]   http://www.inrs.fr/publications/bdd/fichetox.html
  http://www.inrs.fr/publications/bdd/fichetox/fiche.html?refINRS=FICHETOX_243
• ▲6.  Scientific Committee on Consumer Safety, SCCS, OPINION ON Benzisothiazolinone COLIPA n° P96. European Union. (2012).   http://ec.europa.eu/health/scientific_committees/consumer_safety/opinions/index_en.htm
• ▲7.  Deutsche Forschungsgemeinschaft (DFG), 1,2-Benzisothiazol-3(2H)-one. The MAK Collection for Occupational Health and Safety, Vol. 2. Allemagne : Wiley-VCH Verlag GmbH & Co. KGaA. (2012).   http://onlinelibrary.wiley.com/doi/10.1002/3527600418.mb263433kske0002/pdf
• ▲8.  Chew A.-L. et Maibach H.I., «1,2-benzisothiazolin-3-one (Proxel): irritant or allergen?.» Contact Dermatitis. Vol. 36, p. 131-136. (1997).
• ▲9.  National Academy of Sciences, Acute Exposure Guideline Levels for Selected Airborne Chemicals volume 12. Washington, DC. NATIONAL ACADEMY PRESS. (2012).   http://www.nap.edu/catalog/13377/acute-exposure-guideline-levels-for-selected-airborne-chemicals-volume-12

The [number] refers to the ISST database of the CSST Documentation Center.