WHMIS (Aniline hydrochloride)

Workplace Hazardous Materials Information System

WHMIS 1988 classification - Note to reader
Update: 1993-03-20
  • WHMIS pictogram : Skull and crossbones

    D1B

D1B
  • Toxic Material Causing Immediate and Serious Toxic Effects 1
  • Transportation of Dangerous Goods: class 6.1 group III

Disclosure at 1,0% according to the Ingredient disclosure list

WHMIS 2015 classification - Note to reader
Update: 2016-11-22

  • Acute toxicity - oral - Category 42 3
  • Serious eye damage/eye irritation - Category 2A
  • Skin sensitization - Category 14
  • Germ cell mutagenicity - Category 25 6 7 8
  • Specific target organ toxicity - single exposure - Category 14 5 6 9
  • Specific target organ toxicity - repeated exposure - Category 210 11

  • GHS pictogram : Exclamation mark

  • GHS pictogram : Health hazard

Danger

Harmful if swallowed (H302)
Causes serious eye irritation (H319)
May cause allergic skin reaction (H317)
Suspected of causing genetic defects (H341)
Causes damage to organs (H370)
May cause damage to organs through prolonged or repeated exposure (H373)

Comments: Due to the lack of data, classification regarding eye irritation (H319) and skin sensitization (H317) were established by analogy to aniline.

References

  • ▲1.  Canada. Ministère des transports, Règlement sur le transport des marchandises dangereuses. Ottawa : Éditions du gouvernement du Canada. (2014). [RJ-410222]   http://www.tc.gc.ca/fra/tmd/clair-menu-497.htm
    http://www.tc.gc.ca/tmd/menu.htm
  • ▲2.  National Institute for Occupational Safety and Health, RTECS (Registry of Toxic Effects of Chemical Substances). Hamilton (Ont) : Canadian Centre for Occupational Health and Safety.   http://ccinfoweb.ccohs.ca/rtecs/search.html
  • ▲3.  BGIA-Gestis, Information system on hazardous substances of the Berufsgenossenschaften. Sankt Augustin, Germany : Berufsgenossenschaftliches Institut.   http://www.hvbg.de/e/bia/fac/stoffdb/index.html
  • ▲4.  Bureau européen des substances chimiques, European Union Risk Assessment Report : Aniline. 1st Priority List, Vol. 50. Allemagne : Office for Official Publications of the European Communities. (2004).   http://ecb.jrc.ec.europa.eu/esis/ Rechercher le CAS et sélectionner "Final RAR -View and save it" dans le bas de la page.
  • ▲5.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
  • ▲6.  George, E., Andrew, M. et Wstmoreland, C., «Effects of azobenzene and aniline in the rodent bone marrow micronucleus test.» Carcinogenesis. Vol. 11, no. 9, p. 1551-1555. (1990). [AP-001030]
  • ▲7.  Bomhard, E.M, «High-dose clastogenic activity of aniline in the rat bone marrow and its relationship to the carcinogenicity in the spleen of rats..» Archives of Toxicology. Vol. 77, p. 291-297. (2003). [AP-001031]
  • ▲8.  Witt, K.L., Knapton, A. et Wehr, C. M., «Micronucleated erythrocyte frequency in peripheral blood of B6C3F1 mice from short-term, prechronic, and chronic studies of the NTP carcinogenesis bioassay program..» Environmental and Molecular Mutagenesis. Vol. 36, p. 163-194. (2000).
  • ▲9.  Khan, M.F. et al., «Acute hematopoietic toxicity of aniline in rats.» Toxicology Letters. Vol. 92, p. 31-37. (1997). [AP-001033]
  • ▲10.  PRICE, C.J. et al., «TERATOLOGIC AND POSTNATAL EVALUATION OF ANILINE HYDROCHLORIDE IN THE FISCHER 344 RATS .» Toxicology and Applied Pharmacology. Vol. 77, p. 465-478. (1985). [AP-034108]
  • ▲11.  Khan, M.F., «Subchronic toxicity of aniline hydrochloride in rats.» Archives of Environmental Contamination and Toxicology. Vol. 24, p. 368-374. (1993). [AP-001034]

The [number] refers to the ISST database of the CSST Documentation Center.