WHMIS (Acetonitrile)

Workplace Hazardous Materials Information System

WHMIS 1988 classification - Note to reader
Update: 2002-04-15
  • WHMIS pictogram : Flame

    B2

  • WHMIS pictogram : Skull and crossbones

    D1A, D2B

B2
  • Flammable Liquid 1
  • flash point = 5,66 °C Tag closed cup
D1A
  • Very Toxic Material Causing Immediate and Serious Toxic Effects 2
  • acute lethality: LC50 inhalation/4 hours (mouse) =1346 ppm
D2B
  • Toxic Material Causing Other Toxic Effects 3
  • eye irritation in animals

Disclosure at 0,1% according to the Ingredient disclosure list

WHMIS 2015 classification - Note to reader
Update: 2015-08-05

  • Flammable liquids - Category 24
    • Flash point = 6 °C Setaflash closed cup and boiling point = 82 °C
  • Acute toxicity - oral - Category 3
  • Acute toxicity - dermal - Category 43 5 6
  • Acute toxicity - inhalation - Category 32 5 7 8 9 10
  • Serious eye damage/eye irritation - Category 2A11 12

  • GHS pictogram : Flame

  • GHS pictogram : Skull and crossbones

  • GHS pictogram : Exclamation mark

Danger

Highly flammable liquid and vapour (H225)
Toxic if swallowed (H301)
Harmful in contact with skin (H312)
Toxic if inhaled (H331)
Causes serious eye irritation (H319)

References

  • ▲1.  National Institute for Occupational Safety and Health, NIOSH pocket guide to chemical hazards. Washington, D.C. : NIOSH. (2010).   http://www.cdc.gov/niosh/npg/
  • ▲2.  Willhite, C.C., «Inhalation toxicology of acute exposure to aliphatic nitriles.» Clinical Toxicology. Vol. 18, no. 8, p. 991-1003. (1981). [AP-060819]
  • ▲3.  Smyth, H.F. et Carpenter, C.P., «Further experience with the range finding test in the industrial toxicology laboratory.» Journal of Industrial Hygiene and Toxicology. Vol. 30, no. 1, p. 63-68. (1948). [AP-021359]
  • ▲4.  Lenga, R.E. et Votoupal, K.L., The Sigma-Aldrich library of regulatory and safety data. Vol. 1. Milwaukee : Sigma-Aldrich. (1993). [RM-515040]
  • ▲5.  Pozzani, U.C. et al., «An Investigation of the Mammalian Toxicity of Acetonitrile.» Journal of Occupational Medicine. [AP-023886]
  • ▲6.  Parent, R.A., «Acute Toxicity Data Submissions.» Internationnal Journal of Toxicology. Vol. 19, p. 331-373. (2000). [AP-060824]
  • ▲7.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
  • ▲8.  National Institute for Occupational Safety and Health, RTECS (Registry of Toxic Effects of Chemical Substances). Hamilton (Ont) : Canadian Centre for Occupational Health and Safety.   http://ccinfoweb.ccohs.ca/rtecs/search.html
  • ▲9.  France. Institut national de recherche et de sécurité, Fiche toxicologique no 104 : Acétonitrile. Cahiers de notes documentaires. Paris : INRS. (2004). [RE-005509]   http://www.inrs.fr/publications/bdd/fichetox.html
    http://www.inrs.fr/publications/bdd/fichetox/fiche.html?refINRS=FICHETOX_104
  • ▲10.  Pozzani, U.C., Weil, C.S. et Carpenter, C.P., «The toxicological basis of threshold limit values : 5. the experimental inhalation of vapors mixtures by rats, with notes upon the relationship between single dose inhalation and single dose oral data.» American Industrial Hygiene Association Journal. Vol. 20, p. 364-369. (1959). [AP-023711]
  • ▲11.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
  • ▲12.  Bureau européen des substances chimiques, Union Risk Assessment Report : acetonitrile. 1st Priority List, Vol. 18. Luxembourg : Office for Official Publications of the European Communities. (2002). EUR 19839 EN.   http://echa.europa.eu/documents/10162/764c8da5-79e2-418d-bf1f-ab59592f8cc6

The [number] refers to the ISST database of the CSST Documentation Center.