WHMIS (1,2-Diaminoethane)

Workplace Hazardous Materials Information System

WHMIS 1988 classification - Note to reader
Update: 2002-05-09
  • WHMIS pictogram : Flame

    B2

  • WHMIS pictogram : Skull and crossbones

    D1B, D2A, D2B

  • WHMIS pictogram : Corrosion

    E

B2
  • Flammable Liquid 1
  • flash point =34 °C closed cup (non reported method)
D1B
  • Toxic Material Causing Immediate and Serious Toxic Effects 2
  • acute lethality: LD50 oral (guinea pig) = 470 mg/kg
D2A
  • Very Toxic Material Causing Other Toxic Effects 3 4
  • respiratory tract sensitization in humans
D2B
  • Toxic Material Causing Other Toxic Effects 5 6
  • skin sensitization in humans
E
  • Corrosive Material 7
  • Transportation of Dangerous Goods: class 8

Disclosure at 0,1% according to the Ingredient disclosure list

WHMIS 2015 classification - Note to reader
Update: 2015-08-19

  • Flammable liquids - Category 38 9
    • Flash point = 34 °C Setaflash closed cup
  • Acute toxicity - oral - Category 410 11 12 13
  • Acute toxicity - dermal - Category 310 11 12 13 14
  • Acute toxicity - inhalation - Category 410 11 12 15
  • Skin corrosion/irritation - Category 1B10 11 12 13
  • Serious eye damage/eye irritation - Category 110 11 12 16 17
  • Respiratory sensitization - Category 111 13 18
  • Skin sensitization - Category 111 13
  • Specific target organ toxicity - repeated exposure - Category 210 11 13
  • Health hazards not otherwise classified (corrosion) - Category 111 13

  • GHS pictogram : Flame

  • GHS pictogram : Skull and crossbones

  • GHS pictogram : Corrosion

  • GHS pictogram : Health hazard

Danger

Flammable liquid and vapour (H226)
Harmful if swallowed (H302)
Toxic in contact with skin (H311)
Harmful if inhaled (H332)
Causes severe skin burns and eye damage (H314)
May cause allergy or asthma symptoms or breathing difficulties if inhaled (H334)
May cause allergic skin reaction (H317)
May cause damage to organs through prolonged or repeated exposure (H373)
Causes severe damage to the respiratory tract

Ingredient disclosure

Comments12 : Available data indicate that the LC50 of Ethylenediamine is in between 2000 and 4000 ppm/8H ( 6.95 à 13.91mg/L/4H). Inhalation acute toxicity (H332) classification was established with 4000ppm/8H

References

  • ▲1.  National Fire Protection Association, Fire protection guide to hazardous materials. 13th ed. Quincy, Mass. : NFPA. (2002). [RR-334001]
  • ▲2.  Smyth, F.H., Seaton, J. et Fischer, L., «The single dose toxicity of some glycols and derivatives.» Journal of Industrial Hygiene and Toxicology. Vol. 23, no. 6, p. 259-268. (1941). [AP-021581]
  • ▲3.  Nakazawa, T. et Matsui, S., «Ethylenediamine-induced late asthmatic responses.» Journal of Asthma. Vol. 27, no. 4, p. 207-212. (1990).
  • ▲4.  Gelfand, H.H., «Respiratory allergy due to chemical compounds encountered in the rubber, lacquer, shellac and beauty culture industries .» Journal of Allergy. Vol. 34, no. 4, p. 374-381. (1963). [AP-030172]
  • ▲5.  Crow, K.D., Peachey, R.D.G. et Adams, J.E., «Coolant oil dermatitis due to ethylenediamine.» Contact Dermatitis. Vol. 4, p. 359-361. (1978). [AP-017787]
  • ▲6.  Matthieu, L. et al., «Occupational contact sensitization to ethylenediamine in a wire-drawing factory.» Contact Dermatitis. Vol. 29, no. 1, p. 39. (1993).
  • ▲7.  Canada. Ministère des transports, Règlement sur le transport des marchandises dangereuses. Ottawa : Éditions du gouvernement du Canada. (2014). [RJ-410222]   http://www.tc.gc.ca/fra/tmd/clair-menu-497.htm
    http://www.tc.gc.ca/tmd/menu.htm
  • ▲8.  Lenga, R.E. et Votoupal, K.L., The Sigma-Aldrich library of regulatory and safety data. Vol. 1. Milwaukee : Sigma-Aldrich. (1993). [RM-515040]
  • ▲9.  Royal Society of Chemistry (Grande-Bretagne), Chemical safety data sheets : corrosives and irritants. Vol. 3. Cambridge, Angleterre : The Royal Society of Chemistry. (1990). [RM-515064]
  • ▲10.  American Conference of Governmental Industrial Hygienists, Documentation of the threshold limit values and biological exposure indices / Documentation of TLV's and BEI's. 7th ed. Cincinnati, Ohio : ACGIH. (2001-). Publication #0100Doc. [RM-514008]   http://www.acgih.org
  • ▲11.  Centre canadien d'hygiène et de sécurité au travail, CHEMINFO, Hamilton, Ont. : Canadian Centre for Occupational Health and Safety   http://ccinfoweb.ccohs.ca/cheminfo/search.html
  • ▲12.  Smyth, H.F. Jr., Carpenter, C.P. et Weil, C.S., «Range-finding toxicity data : list IV.» Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, p. 119-122. (1951). [AP-060583]
  • ▲13.  BGIA-Gestis, Information system on hazardous substances of the Berufsgenossenschaften. Sankt Augustin, Germany : Berufsgenossenschaftliches Institut.   http://www.hvbg.de/e/bia/fac/stoffdb/index.html
  • ▲14.  National Institute for Occupational Safety and Health, RTECS (Registry of Toxic Effects of Chemical Substances). Hamilton (Ont) : Canadian Centre for Occupational Health and Safety.   http://ccinfoweb.ccohs.ca/rtecs/search.html
  • ▲15.  International Programme on Chemical Safety, 1,2-diaminoethane (ethylenediamine). Concise International Chemical Assessment . Genève : World Health Organization. (1999). CICAD 15.   http://www.inchem.org/pages/cicads.html
  • ▲16.  Grant, W.M. et Schuman, J.S., Toxicology of the eye : effects on the eyes and visual systems from chemicals, drugs, metals and minerals, plants, toxins and venoms; also, systemic side effects from eye medications. Vol. 1, 4th ed. Springfield (ILL.) : Charles C. Thomas. (1993). [RM-515030]
  • ▲17.  OECD, «Ethylenediamine CAS N°: 107-15-3.» In: OECD Screening Information Data Set (SIDS) for High Production Volume Chemicals. Paris : UNEP Publicat.   http://www.inchem.org/pages/search.html http://www.inchem.org/documents/sids/sids/Ethylenediamine.pdf http://www.chem.unep.ch/irptc/sids/OECDSIDS/sidspub.html
  • ▲18.  Andersson, E. et Järvholm, B., «110. Diethylamine, Diethylentriamine, Dimethylamine and Ethylenediamine. Nordic Expert Group for Criteria Documentation of Health Risks from Chemicals.» Arbete Och Halsa. , no. 23. (1994).

The [number] refers to the ISST database of the CSST Documentation Center.